Treatments & Research

Umbilical cord blood stem cells are used in the treatment of over 80 medical conditions. There are many more therapies under clinical trials that are changing the landscape of future medicine:

  • Treatments using cord blood stem cells
  • Treatments using cord tissue stem cells
  • Future Applications of Cord Blood Stem Cells

Leukemia is a cancer of the blood immune system, where the cells are called leukocytes or white cells

  1. Acute Lymphoblastic Leukemia (ALL)
  2. Acute Myelogenous Leukemia (AML)
  3. Acute Biphenotypic Leukemia
  4. Acute Undifferentiated Leukemia
  5. Chronic Lymphocytic Leukemia (CLL)
  6. Chronic Myelogenous Leukemia (CML)
  7. Juvenile Chronic Myelogenous Leukemia (JCML)
  8. Juvenile Myelomonocytic Leukemia (JMML)

Myelodysplastic Syndromes are also called pre-leukemia

  1. Refractory Anemia
  2. Refractory Anemia with Ringed Sideroblasts
  3. Refractory Anemia with Excess Blasts
  4. Refractory Anemia with Excess Blasts in Transformation
  5. Chronic Myelomonocytic Leukemia

Lymphoma is a cancer of the leukocytes that circulate in the blood and lymph vessels

  1. Hodgkin's Lymphoma
  2. Non-Hodgkin's Lymphoma

Other Disorders of Blood Cell Proliferation

  1. Anemias
  2. Aplastic Anemia
  3. Fanconi Anemia
  4. Congenital Dyserythropoietic Anemia
  5. Paroxysmal Nocturnal Hemoglobinuria
  6. Inherited Red Cell Abnormalities
  7. Sickle Cell Disease
  8. Beta Thalassemia Major
  9. Diamond-Blackfan Anemia
  10. Pure Red Cell Aplasia
  11. Inherited Platelet Abnormalities
  12. Amegakaryocytosis / Congenital Thrombocytopenia
  13. Glanzmann Thrombasthenia
  14. Inherited Immune System Disorders
  15. SCID with Adenosine Deaminase Deficiency
  16. SCID with Adenosine Deaminase Deficiency
  17. SCID which is X-linked
  18. SCID with absence of T & B Cells
  19. SCID with absence of T Cells, Normal B Cells
  20. 20. Omenn Syndrome
  21. Inherited Immune System Disorders: Neutropenias
  22. Infantile Genetic Agranulocytosis
  23. Myelokathexis
  24. Inherited Immune System Disorders: Other
  25. Ataxia-Telangiectasia
  26. Bare Lymphocyte Syndrome
  27. Common Variable Immunodeficiency
  28. DiGeorge Syndrome
  29. Hemophagocytic Lymphohistiocytosis
  30. Leukocyte Adhesion Deficiency
  31. Lymphoproliferative Disorders
  32. Lymphoproliferative Disorder, X-linked
  33. Wiskott-Aldrich Syndrome
  34. Myeloproliferative Disorders
  35. Acute Myelofibrosis
  36. Agnogenic Myeloid Metaplasia
  37. Polycythemia Vera
  38. Essential Thrombocythemia
  39. Phagocyte Disorders
  40. Chediak-Higashi Syndrome
  41. Chronic Granulomatous Disease
  42. Neutrophil Actin Deficiency
  43. Reticular Dysgenesis
  44. Bone Marrow Cancers
  45. Multiple Myeloma
  46. Plasma Cell Leukemia
  47. Waldenstrom's Macroglobulinemia

Transplants for Inherited Disorders of the Immune System & Other Organs

  1. Cartilage-Hair Hypoplasia
  2. Erythropoietic Porphyria
  3. Hermansky-Pudlak Syndrome
  4. Pearson's Syndrome
  5. Shwachman-Diamond Syndrome
  6. Systemic Mastocytosis

Transplants for Inherited Metabolic Disorders

  1. Mucopolysaccharidosis (MPS) Storage Diseases
  2. Hurler Syndrome (MPS-IH)
  3. Scheie Syndrome (MPS-IS)
  4. Hunter Syndrome (MPS-II)
  5. Sanfilippo Syndrome (MPS-III)
  6. Morquio Syndrome (MPS-IV)
  7. Maroteaux-Lamy Syndrome (MPS-VI)
  8. Sly Syndrome (MPS-VII) (beta-glucuronidase deficiency)
  9. Mucolipidosis II (I-cell Disease)
  10. Leukodystrophy Disorders
  11. Adrenoleukodystrophy (ALD)
  12. Krabbe Disease(Globoid Cell Leukodystrophy)
  13. Metachromatic Leukodystrophy
  14. Pelizaeus-Merzbacher Disease
  15. Lysosomal Storage Diseases
  16. Niemann-Pick Disease
  17. Sandhoff Disease
  18. Wolman Disease
  19. Other Inherited Metabolic Disorders
  20. Lesch-Nyhan Syndrome
  21. Osteopetrosis

Solid tumors not originating in the blood or immune system

  1. Neuroblastoma
  2. Medulloblastoma
  3. Retinoblastoma

Neurologic Disorders

  1. Autism
  2. Cerebral Palsy
  3. Hearing Loss
  4. Hypoxic Ischemic Encephalopathy
  5. Spinal Cord Injury

Autoimmune Disorders

  1. Amyotrophic Lateral Sclerosis
  2. Crohn's Disease
  3. Diabetes, Type 1
  4. Graft-versus-Host Disease
  5. Kidney plus stem cell transplant
  6. Lupus
  7. Multiple Sclerosis
  8. Rheumatoid Arthritis
  9. Scleroderma

Cardiovascular Disorders

  1. Congenital Defects
  2. Support for Misc. Open Cardiac Surgery
  3. Hypoplastic Left Heart Syndrome (HLHS)
  4. Grow Vascular Graft
  5. Ischemia
  6. Critical Limb Ischemia
  7. Compartment Syndrome (Battlefield Trauma)
  8. Ischemic Stroke
  9. Ischemic Heart Disease
  10. Cardiac Repair
  11. Myocardial Infarction
  12. Cardiomyopathy

Gene Therapy for Inherited Disorders

  1. Adrenoleukodystrophy
  2. Chronic Granulomatous Disease (X-linked)
  3. Fanconi Anemia
  4. HIV
  5. Metachromatic Leukodystrophy
  6. Severe Combined Immunodeficiency
  7. Sickle Cell
  8. Thalassemia
  9. Wiskott-Aldrich Syndrome

Orthopedic Disorders

  1. Alveolar Cleft Palate Repair
  2. Knee Cartilage Repair

Miscellaneous

  1. Bronchopulmonary Dysplasia (BPD)
  2. Epidermolysis Bullosa
  3. HIV aka "AIDS"
  4. Lysosomal Storage Diseases

Source: Parents guide to cord blood

Over 30 clinical trials around the world are researching the capability of these stem cells in treating:

  1. Stroke
  2. Spinal cord injury
  3. Liver disease
  4. Diabetes
  5. Cartilage injury

    Going Beyond 80: More Conditions To Be Treated By Cord Blood Stem Cells

    • Cord blood stem cells are being researched upon for the treatment of conditions such as Autism, traumatic brain injury, congenital heart defects, hearing loss and cerebral palsy. http://parentsguidecordblood.org/trials.php

    Cord Blood Stem Cells For Young & Old: Technology for Cord Blood Stem Cells Expansion Here

    • Technology for expansion of cord blood cells is nearing clinical reality which will enable the possibility of expanding cord blood stem cells up to 200 times thereby providing the possibility of using them in adulthood and also multiple times.

    Gene correcting cord blood stem cells