According to the 2014 world cancer report, gastric cancer is currently the 3rd leading cause of death globally. The survival rate seen in 20% of the patients diagnosed with gastric cancer is less than five years.
Gastric cancer is highly related to eating habits, genetic predisposition, and due to certain stomach diseases.
Existing & New Treatment of Gastric Cancer
The first line of treatment generally used for gastric cancer is surgery, radiotherapy, and chemotherapy.
In recent years with the rapid development of cellular immunotherapy and the shortcomings of prevalent traditional therapies, different types of white blood cells (lymphokine-activated killer cells and cytokine-induced killer cells) are being used effectively for treating such cancers.
Cord blood-derived cells plus a type of white blood cells (cytokine-induced killer cells) combined with chemotherapy proven effective & safe for advanced stomach cancer.
This study was done to prove the efficacy of cord blood derivatives and cytokine-induced killer cells, along with chemotherapy over the patients treated for gastric cancer with only chemotherapy. Based on the studies done to prove, cord blood derivatives were easily obtained and expanded in-vitro, causing the death of a variety of tumors, this study was undertaken.
Details About the Research
A total of 28 patients were recruited for the study with 15 patients to be treated with chemotherapy alone and the rest with this novel combination therapy.
The treatment commenced, and the patients were followed after the procedure for two years. The overall response rate and the disease-free survival rate were tracked closely. Cord blood with lower immune response showed a very low risk of graft versus host disease too.
Earlier researchers used only peripheral blood-derived cells to treat lung cancer, breast cancer, and colon cancer. Since the retrieval of peripheral blood from older patients was difficult, and the number of T-lymphocytes (anti-tumor cells) was not sufficient enough in cancer patients with poor health status, cord blood was an excellent alternative.
The curative effect monitored showed 38.5% in patients with only chemo and 84.6% in patients with cord blood derivative sources. The patients with the combined cord blood derivative treatment also witnessed a longer term of disease-free survival rates, which was remarkable.
The study showed that the cord blood derivatives combined with chemotherapy were not only effective but also safe for patients suffering from advanced stage of gastric cancer.
Current Development on Cord Blood Banking
Presently, cord blood banking is used to treat over 80 medical conditions, including blood disorders, immune disorders, metabolic disorders, and cancers. Also, there are over 500 clinical research underway to determine the role of cord blood stem cells in the treatment of Autism, Cerebral Palsy, Stroke, Diabetes, etc. Umbilical Cord Blood Banking
Cord blood can be preserved at the time of a child’s birth. The blood can be cryo-preserved for a prolonged period and can be used to extract stem cells at the time of need.
LifeCell is India’s premier stem cell bank with over 15 years of industry experience and is trusted by over 3,00,000 happy parents.
Call 1800 266 5533 or SMS “LIFECELL” to 53456 for more information.
This article was published in the Dove Press Journal of Onco Targets and Therapy, 25 July 2016