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18 Dec 2014 0 Comments

Soon, human trials for umbilical cord stem cell research on Lupus

Adult stem cell research on Lupus is making immense progress. The researchers at the Medical University of South Carolina (MUSC) have been able to get a planning grant from the National Institutes of Health to prepare for human trials. This is following studies done in Asia that are revealing that mesenchymal stem cells retrieved from the umbilical cord are effective in treating Lupus.

Lupus is an auto-immune disorder in which the body’s immune system is unable to differentiate between antigens (foreign objects and mirco-organisms) and its own tissues. Autoantibodies develop inside the body and these attack and destroy healthy tissue causing inflammation, pain and damage to different parts of the body.

Researchers have tested in the laboratory, the abilities of mesenchymal stem cells retrieved from both the umbilical cord and bone marrow of lupus affected individuals, to determine which type was more effective in modulating B cell functions. The studies showed that adult stem cells retrieved from the umbilical cord suppressed lupus B cell proliferation, while stem cells from the bone marrow did not suppress B cell proliferation.

These studies were presented at the American College of Rheumatology’s Annual Meeting by researchers from Medical University of South Carolina (MUSC). This data has helped MUSC to get a planning grant from the National Institutes of Health to prepare for future human clinical trials.

The role of mesenchymal stem cells in regenerative medicine is being studied extensively through several clinical trials across the world. Find out which are the other medical conditions that stem cells have the potential to treat: http://www.lifecell.in/promise-of-stemcells.aspx

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