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Trying To Conceive: What To Do After A Year Of No Success

Written By Pooja Rajesh - March 04, 2025
Read Time - 4 min read

Trying to conceive can be an emotionally challenging journey for many couples. While some are lucky enough to conceive quickly, others may face obstacles that prevent them from achieving their dream of parenthood. If you and your partner have been trying to conceive for over a year without success could be indicative of infertility, a common condition among couples.

The truth is that infertility affects millions of couples worldwide, with up to 15% of couples struggling to conceive.1 Infertility is defined as the inability to conceive after 12 months of regular unprotected sex.2 However, this does not mean that you should lose hope. There are many potential reasons for not getting pregnant, and modern medicine has a range of effective treatments available. 

Here are some possible reasons why you might be having trouble conceiving and what you can do about it.

Why Am I Not Getting Pregnant When Everything Is Normal

  • Genetics Can Play A Role

According to a recent study, genetics can be one of the reasons for not getting pregnant.3 The study found that certain genes can influence the success rate of IVF treatment, a popular fertility treatment.4 The research suggests that certain genetic variations may affect egg quality and the receptivity of the uterus, both of which are crucial for successful conception.4 While genetics alone may not be the sole cause of infertility, it is worth discussing with your doctor to determine if genetic testing is a viable option.

  • Age Can Impact Fertility 

A woman's age is a significant factor when it comes to fertility.5 As women age, their ovarian reserve, or the number of viable eggs in their ovaries, decreases.5 This can result in a lower chance of conceiving and a higher risk of pregnancy complications.5 

While there is no way to stop the aging process, there are treatments available to increase the chances of conception. Women who are over 35 and have been trying to conceive should consider speaking with a fertility specialist to discuss their options.5

  • Lifestyle Factors & Their Impact On Fertility

Several lifestyle factors can impact fertility, including smoking, excessive alcohol consumption, and obesity.6 Smoking has been linked to decreased fertility in both men and women, while alcohol can negatively affect sperm count and quality.6 Obesity can also affect fertility, as it can lead to hormonal imbalances that interfere with ovulation.6 Making healthy lifestyle choices, such as quitting smoking, reducing alcohol intake, and maintaining a healthy weight, can increase the chances of conception.6

  • Medical Challenges To Conceive

Certain medical conditions can interfere with fertility, including polycystic ovary syndrome (PCOS), endometriosis, and thyroid disorders.7,8 PCOS is a common hormonal disorder that can cause irregular periods and decreased ovulation, while endometriosis can lead to scarring and damage to the reproductive organs.8 Thyroid disorders can also affect fertility by disrupting hormone levels.8 If you have a medical condition that may be impacting your fertility, speaking with a doctor or fertility specialist is crucial to determine the best course of action.

So, If you are someone who is trying to conceive for a year and suspect that the above-mentioned factors may be affecting your fertility, genetic testing can provide valuable information to guide treatment options.

The Power of Genetic Testing In Infertility Diagnosis

If you have been trying to conceive for over a year with no success, it may be time to seek professional help. A fertility specialist can suggest tests to determine the cause of infertility and recommend treatment options. That’s where LifeCell InferGenes- Male and Female can help you! 

LifeCell's InferGenes Female Panel tests 26 genes associated with female health conditions that could cause infertility, while the InferGenes Male Panel tests 36 genes for male infertility conditions. The test can identify genetic root causes of infertility issues, assess reproductive risks, provide insights on possible treatment options, and offer genetic counseling. The female panel analyzes genes affecting egg development, ovarian reserve, hormonal signaling, and reproductive organ development, while the male panel looks at genes impacting sperm production, structure, and transport.

Wrapping Up!

In conclusion, trying to conceive can be a difficult and emotional journey, but it's important to remember that you're not alone. Infertility affects millions of couples, but there are many potential reasons and treatments available. Genetic testing, like LifeCell's InferGenes, can provide valuable information to guide treatment options and help you and your partner on your journey to parenthood. Don't lose hope and remember to seek professional help if you've been trying to conceive for over a year with no success.

Wish to learn more? Click here or call 1800 266 5533.

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